![]() Expression of FREAC-1 and FREAC-2 is restricted to lung and placenta. Cotransfections with a reporter carrying FREAC binding sites showed that both proteins are transcriptional activators, and deletions located the activation domains to the COOH-terminal side of the forkhead domains. FREAC-1 and −2 are encoded by distinct genes, are almost identical within their DNA binding domains and in the COOH termini, but are otherwise divergent. ![]() Freac by pattern Activator#We describe the cDNA sequences for two human transcription factors, Forkhead RElated ACtivator (FREAC)-1 and −2, that belong to the forkhead family of eukaryotic DNA binding proteins.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |